Endocrine Abstracts

A 73-year-old lady with a history of type two diabetes since 1993, mastectomy for carcinoma left breast in 2000, primary hypothyroidism, and hypertension was referred to the local hospital in view of poor glycaemic control in July 2001. Her medications included Thyroxine, Atenolol, and Tamoxifen, Frusemide, Gliclazide 160 mg BD and Pioglitazone 30 mg. At the time of referral her weight was 68.5 kg, (BMI 23.7), HbA1c 10.2%. She was started on Humalog mix 25 BD. In 2003 her weig...

Background: The use of opioids in non-cancer patients has increased dramatically over the past few years. The most common endocrine dysfunction with opioid use is hypogonadism, but it has been reported in a small number of cases that adrenal insufficiency and adult growth hormone deficiency can also occur.Clinical case: A 39 year old male presented with general fatigue, loss of libido and sweating for about six mont...

Background: The use of opioids in non-cancer patients has increased dramatically over the past few years. The most common endocrine dysfunction with opioid use is hypogonadism, but it has been reported in a small number of cases that adrenal insufficiency and adult growth hormone deficiency can also occur.Clinical case: A 39 year old male presented with general fatigue, loss of libido and sweating for about six mont...

Introduction: Despite the commonality of hyponatraemia in everyday clinical medicine it is often a poorly management condition in acute medical patients. A European guideline for diagnosis and management was published in 2014 to address such problems.Aims: To assess the standard of management of patients with hyponatraemia admitted to the medical departments in a rural District General Hospital. To improve investigation, diagnosis, and management of thes...

Introduction: Unilateral adrenalectomy is an effective treatment for aldosterone producing adenoma. However, after adrenalectomy, suppression of the contralateral zona glomerolura (ZG) function can lead to transient hypotension & hyperkalaemia. We present a protracted case of post-operative adrenalectomy related hypoaldosteronism.Case: A 54-year-old hypertensive male with confirmed primary hyperaldoseronism (PRA<0.1 nm/h, aldosterone 1050 pmol/l;...